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2021-2022 Request for Applications

ITHS Translational Pilot Award with a Special Emphasis on Diabetes

ITHS Translational Pilot Award with a Special Emphasis on Diabetes

2021-2022 RFA

ITHS is offering a Translational Pilot Award with a Special Emphasis on Diabetes in conjunction with the Diabetes Research Center to support studies that address impactful research issues within the translational science spectrum, with the long-term goal of improving the health of patients with diabetes.

Examples might include pre-clinical work with animal models, clinical observational or implementation studies, or public health outcomes research related to diabetes and its complications.

This pilot award will provide up to $25,000 in total direct costs for one year. No-cost extensions will not be permitted.

Application Period Closed

Key Dates

The following key dates apply to this funding opportunity:

  • Letter of Intent Deadline
    Date
  • Notice of Invitation to Apply
    Date
  • Application Deadline
    October 9, 2020
  • Awardees Notified
    December 7, 2020
  • Period of Performance
    March 1, 2021 – February 28, 2022

Priority for support will be given to junior investigators at or below the rank of Assistant Professor or equivalent. Established investigators will be considered only if work proposed encompasses a translational project that differs significantly from their current research directions.

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Guidelines
Guidelines
  1. Successful applications will address a critical knowledge gap in type 1 or type 2 diabetes and represents a key step toward improvement in the treatment or prevention of disease. The project must demonstrate significant scientific merit and provide a vision of how it could evolve to a more substantial body of work.Examples of projects that would be considered responsive to this RFA include (but are not limited to):
    • Investigations into basic cellular processes involved in glucose metabolism or the regulation of insulin signaling with the use of in vitro cell culture models or primary cells.
    • Animal studies with dietary, pharmacologic or genetic interventions to improve our understanding of glucose tolerance, insulin sensitivity, pancreatic b-cell function or diabetic complications.
    • Human observational or epidemiological studies to identify risk factors for type 1 or type 2 diabetes or complications of diabetes.
    • Randomized controlled trials of diet or other lifestyle interventions, investigational drugs or devices, or other interventions (e.g. bariatric surgery) to assess their impact on glycemic control, glucose tolerance or complications of diabetes.
  2. Plan to spend your money in 1 year. No-cost extensions will not be allowed. ITHS faculty or staff may be listed as active research contributors on a case-by-case basis. Please consult with ITHS prior to application submission if your proposal includes ITHS faculty or staff.
Eligible Investigators
Eligible Investigators

Faculty members at ITHS Partner Institutions, including the University of Washington, Fred Hutch Cancer Research Center, Seattle Children’s Research Institute, and other academic institutions affiliated with the ITHS in the WWAMI (Washington, Wyoming, Alaska, Montana, Idaho) region are eligible to apply for this pilot award. Collaborations may extend outside the WWAMI region; however, funds may not be transferred outside the United States. ITHS-funded faculty and staff are ineligible to apply. An acting faculty member or instructor is eligible to apply only if the Department head provides a letter supporting the applicant’s eligibility to serve as PI.

All Investigators on the research team must be ITHS Members in order to apply. To become a member, please complete the ITHS Membership Form.

Application Process
Application Process
A. Letter of Intent

The letter of intent form must be submitted through the ITHS website before submission of the application. The form includes information on the applicant and any Co-Investigators or Community Partners, project title, and abstract (250 word maximum). Investigators who are invited to submit a full application will receive notice within two weeks.

A. Application

The application must be submitted through the ITHS website.

Applications will follow National Institutes of Health (NIH) formatting guidelines (see FAQ) and include:

[prettyfilelink size=”95 KB” src=”https://www.iths.org/wp-content/uploads/Cover-Page-Special-Emphasis.2018.pdf” type=”pdf”]1) Cover Page[/prettyfilelink]

2) Project Title and Abstract (250 word maximum)
3) Research Plan, 2-pages (references do not count toward page limit)

[prettyfilelink size=”57 KB” src=”https://www.iths.org/wp-content/uploads/Pilot-Proposal-Timeline-Template.2018.docx” type=”doc”]4) Project Timeline – 1-page[/prettyfilelink]

5) Budget and Budget Justification [prettyfilelink size=”29 KB” src=”https://www.iths.org/wp-content/uploads/Pilot-Budget-Template.2018.xlsx” type=”xls inline”]5a) Budget[/prettyfilelink] [prettyfilelink size=”37 KB” src=”https://www.iths.org/wp-content/uploads/Pilot-Budget-Justification-Sample.2018.docx” type=”doc inline”]5b) Budget Justification[/prettyfilelink]
6) Letter(s) of Support Letters of Support are not required unless you are an instructor or acting faculty member. If you are an instructor or acting faculty member, you will need to include a letter supporting your eligibility to serve as PI from your Department head (or equivalent).

[prettyfilelink size=”35 KB” src=”https://www.iths.org/wp-content/uploads/Biosketch-Sample.2018.docx” type=”doc”]7) NIH format Biosketches for all investigators (senior/key personnel)[/prettyfilelink]

Not included in the above document:

Suggested Reviewers – You will also be asked to provide five suggested reviewers, including the following information for each: 1) Name, 2) Title, 3) Institution/Organization, and  4) Email Address.

A general note about conflict of interest: A reviewer would have a conflict of interest if they are the applicant’s mentor, dept. chair, spouse, or close relative; or if they currently work together on manuscripts, grants, or business ventures. Simply being in the same department or division is not, in and of itself, a conflict of interest.

B. Timeline

  • Letter of Intent Deadline – Date
  • Notice of Invitation to Apply – Date
  • Application Deadline – October 9, 2020
  • Scientific Review – October 2020 – November 2020
  • Awardees Notified – December 7, 2020
  • Just-in-Time Process – December 2020 – February 2021
  • Period of Performance – March 1, 2021 – February 28, 2022

ITHS is funded through a CTSA grant from NIH’s National Center for Advancing Translational Sciences (NCATS). NCATS requires the review and approval of all pilot grants involving human subjects research before funds are released. Therefore, if your proposal is awarded funding and involves human subjects research, additional documentation will be required. NCATS review and IRB review can be concurrent, but final NCATS approval is contingent upon IRB approval.

Frequently Asked Questions
FAQs

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Page last modified: Dec 23, 2020 @ 6:19 am (PST)